MR IMAGING IN ACUTE MARCHIAFAVA-BIGNAMI DISEASE: A CASE REPORT 0 By Giovan Battista Lo Piparo, Alessandro Schiavello, Dario Altieri, Domenico Grisafi, Corrado Reina on December 10, 2008 Capsula eBurnea Abstract. Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism. MBD is characterized by primary demyelination of the corpus callosum. We report one case of MBD in which MR imaging showed high T2 FLAIR and diffusion- weighted signal intensity of the corpus callosum and in the deep and shallow white matter, in particular, of the temporo- occipital and fronto-parietal lobes. Here we describe the clinical case of a 57-year-old male patient, with a 30- year history of alcohol (wine) brought to us in a state of mental confusion. He showed gait disturbance and lack of motor coordination. Alessandro Schiavello Corrado Reina Dario Altieri Domenico Grisafi Giovan Battista Lo Piparo Share. Twitter Facebook Google+ Pinterest LinkedIn Tumblr Email
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